Effect of sprint cycle training on activities of antioxidant enzymes in human skeletal muscle
| Autor: | Fred S. Apple, Ylva Hellsten, Bertil Sjödin |
|---|---|
| Rok vydání: | 1996 |
| Předmět: |
Adult
Male medicine.medical_specialty Antioxidant Anaerobic Threshold Physiology medicine.medical_treatment education Physical exercise Antioxidants Superoxide dismutase Physiology (medical) Internal medicine medicine Humans Muscle Skeletal chemistry.chemical_classification Glutathione Peroxidase biology Superoxide Dismutase Skeletal muscle Bicycling Glutathione Reductase Endocrinology Enzyme medicine.anatomical_structure Sprint chemistry Physical Fitness biology.protein |
| Zdroj: | University of Copenhagen |
| ISSN: | 1522-1601 8750-7587 |
| DOI: | 10.1152/jappl.1996.81.4.1484 |
| Popis: | Hellsten, Ylva, Fred S. Apple, and Bertil Sjödin.Effect of sprint cycle training on activities of antioxidant enzymes in human skeletal muscle. J. Appl. Physiol. 81(4): 1484–1487, 1996.—The effect of intermittent sprint cycle training on the level of muscle antioxidant enzyme protection was investigated. Resting muscle biopsies, obtained before and after 6 wk of training and 3, 24, and 72 h after the final session of an additional 1 wk of more frequent training, were analyzed for activities of the antioxidant enzymes glutathione peroxidase (GPX), glutathione reductase (GR), and superoxide dismutase (SOD). Activities of several muscle metabolic enzymes were determined to assess the effectiveness of the training. After the first 6-wk training period, no change in GPX, GR, or SOD was observed, but after the 7th week of training there was an increase in GPX from 120 ± 12 (SE) to 164 ± 24 μmol ⋅ min−1 ⋅ g dry wt−1( P < 0.05) and in GR from 10.8 ± 0.8 to 16.8 ± 2.4 μmol ⋅ min−1 ⋅ g dry wt−1( P < 0.05). There was no significant change in SOD. Sprint cycle training induced a significant ( P < 0.05) elevation in the activity of phosphofructokinase and creatine kinase, implying an enhanced anaerobic capacity in the trained muscle. The present study demonstrates that intermittent sprint cycle training that induces an enhanced capacity for anaerobic energy generation also improves the level of antioxidant protection in the muscle. |
| Databáze: | OpenAIRE |
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