| Autor: |
Olga, Potapińska, Urszula, Demkow, Maria, Wasik |
| Rok vydání: |
2009 |
| Předmět: |
|
| Zdroj: |
Advances in Respiratory Medicine. 77:152-158 |
| ISSN: |
2543-6031 |
| DOI: |
10.5603/arm.27831 |
| Popis: |
For several years the incidences of allergic diseases and anaphylactic reactions have been increasing dramatically. Classical method of allergy diagnosis—skin prick test in some situations can provoke life-threatening reactions. Detection of allergen-induced basophil activation by flow cytometry has been shown to be a useful tool for allergy diagnosis in those patients. CD 63 and CD203c have recently been demonstrated as a specific activation markers of basophils that are rapidly up-regulated after allergen challenge in sensitized patients. Although flow-cytometry methods are quite sophisticated and expensive, it could be a good alternative in patients at risk of severe anaphylactic reactions or with contradictory test results. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
