Clinical description and follow-up investigation of human West Nile virus cases
| Autor: | Kristy L. Gottfried, Robbie Quinn, Timothy F. Jones |
|---|---|
| Rok vydání: | 2005 |
| Předmět: |
Adult
Male Weakness Pediatrics medicine.medical_specialty Adolescent viruses Virus Flaviviridae medicine Humans Meningitis Longitudinal Studies Fatigue Aged Retrospective Studies Aged 80 and over Memory Disorders Movement Disorders Muscle Weakness biology business.industry Medical record Retrospective cohort study General Medicine Recovery of Function Length of Stay Middle Aged medicine.disease biology.organism_classification Prognosis Tennessee Flavivirus Immunology Encephalitis Female medicine.symptom business West Nile Fever Follow-Up Studies |
| Zdroj: | Southern medical journal. 98(6) |
| ISSN: | 0038-4348 |
| Popis: | Objectives: The objective of this study was to investigate long-term outcomes after West Nile virus infection. Methods: We reviewed the medical records of persons reported with West Nile virus in Tennessee in 2002 and interviewed cases 1 year after acute illness. Results: In 2002, 56 cases of West Nile virus were reported in Tennessee; 48 (84%) had meningitis or encephalitis. Of those, 9 (19%) died during acute infection and 12 (25%) died within 6 months of illness onset. Patients with West Nile virus neurologic illness spent a median of 10 days in the hospital and were unable to resume normal activities for a median of 25 days. One year later, 12 of 22 (55%) persons reported that they were not fully recovered, with symptoms including fatigue, weakness, difficulty ambulating, and memory problems. Conclusions: West Nile virus infection leads to high rates of mortality and substantial persistent morbidity. Prevention efforts should be targeted to populations at highest risk of severe sequelae. |
| Databáze: | OpenAIRE |
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