Twenty-year experience with salvage total laryngectomy: lessons learned
| Autor: | Marios Stavrakas, Angelos Nikolaou, K Vlachtsis, N Tsetsos, Georgios Fyrmpas, A Poutoglidis |
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| Rok vydání: | 2021 |
| Předmět: |
Male
medicine.medical_specialty Glottis medicine.medical_treatment Laryngectomy Kaplan-Meier Estimate Pharyngocutaneous Fistula 03 medical and health sciences 0302 clinical medicine medicine Humans In patient Stage (cooking) 030223 otorhinolaryngology Laryngeal Neoplasms Aged Retrospective Studies Salvage Therapy business.industry Neck dissection General Medicine Middle Aged Survival Analysis Surgery Radiation therapy medicine.anatomical_structure Otorhinolaryngology 030220 oncology & carcinogenesis Female business Chemoradiotherapy |
| Zdroj: | The Journal of Laryngology & Otology. 135:729-736 |
| ISSN: | 1748-5460 0022-2151 |
| Popis: | ObjectiveThe purpose of this study was to evaluate the outcome of salvage total laryngectomy and identify areas for further improvement.MethodA retrospective analysis of all patients who underwent salvage total laryngectomy between January 1999 and December 2018 was performed.ResultsThirty-one patients were identified. The most common primary tumour site was the glottis (83.8 per cent). Early stage (T1–T2) disease was identified in 83.9 per cent of cases. Overall survival at 2 and 5 years post-salvage total laryngectomy was 71 per cent and 45 per cent, respectively. Disease-free survival at 2 and 5 years post-salvage total laryngectomy was 65 per cent and 42 per cent, respectively. The rate of post-salvage total laryngectomy pharyngocutaneous fistula was 29 per cent.ConclusionMore than half of patients will not survive beyond five years after salvage total laryngectomy. Regional recurrence was the most common form of failure and death. From this study, elective lateral and central neck dissection is advocated in patients with early laryngeal cancer who present with an advanced recurrence. |
| Databáze: | OpenAIRE |
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