The incidental findings of age-related macular degeneration during diabetic retinopathy screening

Autor: Sarah M. McGhee, RA Gangwani, David Wong, Anthony J. Hedley, Rita Sum, Catherine W S Chan, Wico W. Lai
Rok vydání: 2013
Předmět:
Zdroj: Graefe's Archive for Clinical and Experimental Ophthalmology. 252:723-729
ISSN: 1435-702X
0721-832X
DOI: 10.1007/s00417-013-2530-1
Popis: The purpose of this study was to determine the reliability of detecting age-related macular degeneration (AMD) during screening for diabetic retinopathy (DR). This prospective study included 2,003 subjects with diabetes mellitus who underwent photographic screening for DR. The reliability of detecting AMD lesions was tested by interobserver and intraobserver agreement, and the sensitivity and specificity of diagnosing AMD at different grades of severity were tested using the consensus grading of a group as the reference standard. DR affected 24.7 % of the subjects. The age-standardized prevalence of early AMD was 17.9 %, and late AMD was 0.1 %. The interobserver and intraobserver agreement for grading AMD was substantial (k = 0.72 and 0.71 respectively, p
Databáze: OpenAIRE