Scandcleft randomized trials of primary surgery for unilateral cleft lip and palate : comparison of dental arch relationships and dental indices at 5, 8, and 10 years
| Autor: | Jeanette Mooney, Sara Rizell, Midia Najar Chalien, Paul Sæle, Kirsten Mølsted, Agneta Karsten, Gunvor Semb, Phil Eyres, Pål Skaare, William C. Shaw, Haydn Bellardie, Arja Heliövaara, Eli Brinck, Annelise Küseler, Agneta Marcusson |
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| Přispěvatelé: | HUS Musculoskeletal and Plastic Surgery, Plastiikkakirurgian yksikkö |
| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: |
medicine.medical_specialty
Index (economics) OCCLUSAL CHARACTERISTICS SCORING SYSTEM Cleft Lip Orthodontics CHILDREN Common method GOSLON YARDSTICK Odontologi MODIFIED HUDDART Surgical methods law.invention 03 medical and health sciences Dental Arch 0302 clinical medicine Cohen's kappa Randomized controlled trial law medicine Humans Child 030223 otorhinolaryngology Trial registration Randomized Controlled Trials as Topic business.industry Reproducibility of Results Goslon yardstick 030206 dentistry 3126 Surgery anesthesiology intensive care radiology 313 Dentistry 3. Good health Surgery Cleft Palate Dental arch Treatment Outcome medicine.anatomical_structure Child Preschool Dentistry GROWTH business |
| Zdroj: | Heliövaara, A, Küseler, A, Skaare, P, Bellardie, H, Mølsted, K, Karsten, A, Marcusson, A, Rizell, S, Brinck, E, Sæle, P, Chalien, M N, Mooney, J, Eyres, P, Shaw, W & Semb, G 2022, ' Scandcleft randomized trials of primary surgery for unilateral cleft lip and palate : comparison of dental arch relationships and dental indices at 5, 8, and 10 years ', European Journal of Orthodontics, vol. 44, no. 3, 055, pp. 258-267 . https://doi.org/10.1093/ejo/cjab055 |
| DOI: | 10.1093/ejo/cjab055 |
| Popis: | Summary Background and trial design The Scandcleft intercentre study evaluates the outcomes of four surgical protocols (common method Arm A, and methods B, C, and D) for treatment of children with unilateral cleft lip and palate (UCLP) in a set of three randomized trials of primary surgery (Trials 1, 2, and 3). Objectives To evaluate and compare dental arch relationships of 5-, 8-, and 10-year-old children with UCLP after four different protocols of primary surgery and to compare three dental indices. The results are secondary outcomes of the overall trial. Methods Study models taken at the ages of 5 (n = 418), 8 (n = 411), and 10 years (n = 410) were analysed by a blinded panel of orthodontists using the Eurocran index, the 5-year-olds’ (5YO) index, and the GOSLON Yardstick. Student’s t-test, Pearson’s correlation, chi-square test, and kappa statistics were used in statistical analyses. Results The reliability of the dental indices varied between moderate and very good, and those of the Eurocran palatal index varied between fair and very good. Significant correlations existed between the dental indices at all ages. No differences were found in the mean 5-, 8-, and 10-year index scores or their distributions within surgical trials. Comparisons between trials detected significantly better mean index scores in Trial 2 Arm C (at all ages) and in Trial 1 Arm B (at 5 and 10 years of age) than in Trial 3 Arm D. The mean Eurocran dental index scores of the total material at 5, 8, and 10 years of age were 2.50, 2.60, and 2.26, and those of the 5YO index and GOSLON Yardstick were 2.77, 2.90, and 2.54, respectively. At age 10 years, 75.8% of the patients had had orthodontic treatment. Conclusions The results of these three trials do not provide evidence that one surgical method is superior to the others. The reliabilities of the dental indices were acceptable, and significant correlations existed between the indices at all ages. The reliability of the Eurocran palatal index was questionable. Trial registration ISRCTN29932826. |
| Databáze: | OpenAIRE |
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