Characteristics and progression of hearing loss in children with turner's syndrome
| Autor: | Alexandra O. Hamberis, Charmee H. Mehta, James R. Dornhoffer, Ted A. Meyer |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Male
Aortic valve Pediatrics medicine.medical_specialty Hearing loss Turner Syndrome Gonadal dysgenesis Severity of Illness Index 03 medical and health sciences 0302 clinical medicine otorhinolaryngologic diseases medicine Humans Child Hearing Loss 030223 otorhinolaryngology Retrospective Studies business.industry Odds ratio medicine.disease Turner's syndrome Confidence interval Conductive hearing loss medicine.anatomical_structure Otitis Otorhinolaryngology Child Preschool Disease Progression Female medicine.symptom business 030217 neurology & neurosurgery |
| Zdroj: | The Laryngoscope. 130:1540-1546 |
| ISSN: | 1531-4995 0023-852X |
| DOI: | 10.1002/lary.28264 |
| Popis: | OBJECTIVES/HYPOTHESIS Evaluate patterns of hearing impairment in children with Turner's syndrome (TS) and determine factors influencing severity and progression. STUDY DESIGN Retrospective database review. METHODS Demographic, audiological, and medical data for children with TS were extracted from the Audiological and Genetic Database to analyze patterns of hearing loss with comorbidities, demographics, and interventions. RESULTS Two hundred seventy-two children with TS were identified; 213 had audiological data. Of these children, 72.3% (N = 154) had hearing loss in which 84.4% (N = 130) was bilateral. In individual ears, conductive hearing loss was most common (28.7%, n = 73), followed by mixed (22.0%, n = 93) and sensorineural (7.9%, n = 20). Otitis media (odds ratio [OR] = 2.7, 95% confidence interval [CI]: 1.2-6.5), eustachian tube dysfunction (OR = 9.5, 95% CI: 3.2-35.2), and aortic valve anomalies were also associated with higher rates of hearing loss (OR = 3.6, 95% CI: 1.3-11.5). Of ears with quantifiable severity, 16.3% (n = 40) had moderate or worse hearing loss. Aortic coarctation (36.3 vs. 21.3 dB, P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text