Transient gestational diabetes insipidus diagnosed in successive pregnancies: review of pathophysiology, diagnosis, treatment, and management of delivery
| Autor: | Alkan Yildirim, Ayse Kubat Uzum, Recep Has, Tülay Özkan, Ibrahim Kalelioglu, Funda Gungor |
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| Rok vydání: | 2007 |
| Předmět: |
Adult
medicine.medical_specialty Endocrinology Diabetes and Metabolism urologic and male genital diseases Preeclampsia Acute fatty liver of pregnancy Endocrinology Polyuria Pregnancy medicine Humans Deamino Arginine Vasopressin Cesarean Section Repeat Desmopressin Fetus business.industry Obstetrics medicine.disease Magnetic Resonance Imaging female genital diseases and pregnancy complications Diabetes Gestational Diabetes insipidus Etiology Female medicine.symptom business Diabetes Insipidus hormones hormone substitutes and hormone antagonists medicine.drug |
| Zdroj: | Pituitary. 10:87-93 |
| ISSN: | 1573-7403 1386-341X |
| Popis: | Gestational diabetes insipidus (GDI) is a rare disorder characterised by polyuria, polydypsia, and excessive thirst usually manifesting in the third trimester of pregnancy. The etiology is thought to depend on excessive vasopressinase activity, a placental enzyme that degrades arginine-vasopressin (AVP), but not 1-deamino-8-D: -arginine vasopressin (dDAVP), which is a synthetic form. This is a transient syndrome and may be associated with acute fatty liver of pregnancy and preeclampsia. The use of dDAVP in symptomatic cases has been proven as a safe method for both the mother and the fetus during the pregnancy. We report a case of recurrent gestational diabetes insipidus in successive pregnancies, which responded to dDAVP and subsided after delivery. |
| Databáze: | OpenAIRE |
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