An atom efficient and solvent-free synthesis of structurally diverse amides using microwaves

Autor:	Edith Gelens, Bart J. van Steen, Luc Smeets, Rob Leurs, Chris G. Kruse, Romano V. A. Orru, Leo A. J. M. Sliedregt
Přispěvatelé:	Organic Chemistry, Medicinal chemistry
Jazyk:	angličtina
Rok vydání:	2005
Předmět:	Solvent free Primary (chemistry) Chemistry Organic Chemistry Atom (order theory) General Medicine Optically active Photochemistry Biochemistry Drug Discovery Atom Organic chemistry SDG 6 - Clean Water and Sanitation Racemization Microwave
Zdroj:	Gelens, E, Smeets, L, Sliedregt, L A, van Steen, B J, Kruse, C G, Leurs, R & Orru, R V A 2005, ' An atom efficient and solvent-free synthesis of structurally diverse amides using microwaves ', Tetrahedron Letters, vol. 46, no. 21, pp. 3751-3754 . https://doi.org/10.1016/j.tetlet.2005.03.146 Tetrahedron Letters, 46(21), 3751-3754. Elsevier Limited
ISSN:	0040-4039
DOI:	10.1016/j.tetlet.2005.03.146
Popis:	An array of structurally diverse amides was synthesized efficiently by combining (primary and secondary) amines and carboxylic acids in one-pot under solvent-free microwave (MW) conditions. In most cases, no racemization was observed with optically active inputs and chiral amides were obtained in high ee or de. © 2005 Elsevier Ltd. All rights reserved.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01c8705cb7f7b5d737e1e12d5171b151 https://doi.org/10.1016/j.tetlet.2005.03.146 Zobrazit plný text záznamu Full Text from ScienceDirect