Risk factors for community-acquired bacterial meningitis

Autor: Thomas Benfield, Lene Fogt Lundbo
Rok vydání: 2017
Předmět:
Adult
Male
0301 basic medicine
Microbiology (medical)
Adolescent
Haemophilus influenzae type
030106 microbiology
Meningitis
Meningococcal
Neisseria meningitidis
medicine.disease_cause
Meningitis
Bacterial
Microbiology
Pathogenesis
03 medical and health sciences
0302 clinical medicine
Risk Factors
Genetic variation
Streptococcus pneumoniae
Humans
Medicine
030212 general & internal medicine
Child
Meningitis
Haemophilus
General Immunology and Microbiology
biology
Meningitis
Pneumococcal
business.industry
Age Factors
Haemophilus influenzae type b
Infant
General Medicine
biology.organism_classification
medicine.disease
Community-Acquired Infections
Infectious Diseases
Socioeconomic Factors
Child
Preschool
Bacterial Vaccines
Host-Pathogen Interactions
Immunology
Female
Bacterial meningitis
business
Meningitis
Bacteria
Zdroj: Infectious Diseases. 49:433-444
ISSN: 2374-4243
2374-4235
DOI: 10.1080/23744235.2017.1285046
Popis: Bacterial meningitis is a significant burden of disease and mortality in all age groups worldwide despite the development of effective conjugated vaccines. The pathogenesis of bacterial meningitis is based on complex and incompletely understood host-pathogen interactions. Some of these are pathogen-specific, while some are shared between different bacteria.We searched the database PubMed to identify host risk factors for bacterial meningitis caused by the pathogens Streptococcus pneumoniae, Neisseria meningitidis and Haemophilus influenzae type b, because they are three most common causative bacteria beyond the neonatal period.We describe a number of risk factors; including socioeconomic factors, age, genetic variation of the host and underlying medical conditions associated with increased susceptibility to invasive bacterial infections in both children and adults.As conjugated vaccines are available for these infections, it is of utmost importance to identify high risk patients to be able to prevent invasive disease.
Databáze: OpenAIRE
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