Scoping Review of Targeted Ultrasound Contrast Agents in the Detection of Angiogenesis
| Autor: | Jennifer E. Dinalo, Marielena Rivas, Vinay Duddalwar, Christopher Lau, Kevin King |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Oncology
Male medicine.medical_specialty Angiogenesis Colorectal cancer Contrast Media 030218 nuclear medicine & medical imaging 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Breast cancer Internal medicine Neoplasms medicine Humans Radiology Nuclear Medicine and imaging Ultrasonography 030219 obstetrics & reproductive medicine Radiological and Ultrasound Technology Neovascularization Pathologic business.industry Ultrasound Cancer medicine.disease Image Enhancement Vascular endothelial growth factor chemistry Microbubbles Female business Systematic search |
| Zdroj: | Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in MedicineReferences. 39(1) |
| ISSN: | 1550-9613 |
| Popis: | A systematic search was conducted to categorize targeted ultrasound contrast agents (UCAs) used in cancer-related angiogenesis detection. We identified 15 unique contrast agents from 2008 to March 2018. Most primary research articles studied UCAs targeted to vascular endothelial growth factor receptor or αv β3 -integrin. Breast cancer and colon cancer are the most common neoplastic processes in which these agents were studied. BR55 (Bracco Research SA, Geneva, Switzerland), a vascular endothelial growth factor receptor-targeting UCA, is the first targeted UCA that has completed phase 0 trials. Our review identifies a gap in the literature regarding the application of targeted UCAs in cancer models beyond breast and colon cancers and identifies other promising UCAs. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text