Effects of altering O2 delivery on VO2 of isolated, working muscle
Autor: | J Delehunt, M Gleser, D H Horstman |
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Rok vydání: | 1976 |
Předmět: |
medicine.medical_specialty
chemistry.chemical_element Blood Pressure Muscle blood flow Oxygen Hemoglobins Dogs Oxygen Consumption Physiology (medical) Internal medicine medicine Animals Gracilis muscle Hypoxia Chemistry musculoskeletal neural and ocular physiology Muscles Respiration VO2 max Limiting Electric Stimulation Endocrinology Biochemistry Regional Blood Flow Oxyhemoglobins Oxygen delivery Hemoglobin Perfusion circulatory and respiratory physiology Muscle Contraction |
Zdroj: | The American journal of physiology. 230(2) |
ISSN: | 0002-9513 |
Popis: | Maximal oxygen consumption (VO2 max) and muscle blood flow (Q max) were measured in an isolated gracilis muscle preparation before and after alteration in perfusion pressure (BP), arterial oxygen saturation (SaO2), and hemoglobin concentration (Hb). Q varied directly with BP and inversely with Hb (viscosity) but was unaffected by changes in arterial SaO2. VO2 max varied directly with oxygen delivery under all conditions. These results indicate that VO2 max is normally limited by oxygen delivery rather than any intrinsic limiting of oxygen consumption of the muscle. |
Databáze: | OpenAIRE |
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