Early‐stage predictors of the acute phase duration in uncomplicated COVID‐19 pneumonia
| Autor: | Giovanni M. Guarrera, C. Carallo, Cesare Tripolino, Susanna Cozzio, Fabiola Pugliese, Chiara Oliveri, Lorenza Lenzi, Giada Fasani, Walter Spagnolli |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Blood Platelets
Male medicine.medical_specialty medicine.medical_treatment medicine.disease_cause SARS‐CoV‐2 hospital resources 03 medical and health sciences 0302 clinical medicine Internal medicine Fraction of inspired oxygen Virology medicine Intubation Humans 030212 general & internal medicine Stage (cooking) Respiratory system Research Articles Coronavirus business.industry SARS-CoV-2 COVID-19 Pneumonia Middle Aged medicine.disease Early warning score hospital stay Hospitalization Infectious Diseases Arterial blood 030211 gastroenterology & hepatology Female disease duration business in‐hospital Research Article COVID‐19 pneumonia |
| Zdroj: | Journal of Medical Virology |
| ISSN: | 1096-9071 0146-6615 |
| Popis: | Objective In this study, we aimed to highlight the common early‐stage clinical and laboratory variables independently related to the acute phase duration in patients with uncomplicated coronavirus disease (COVID‐19) pneumonia. Methods In hospitalized patients, the acute phase disease duration was followed using the Brescia‐COVID respiratory severity scale (BCRSS). Noninvasive ventilation was administered based on clinical judgment. Patients requiring oropharyngeal intubation were excluded from the study. For parameters to be measured at the hospital entrance, age, clinical history, National Early Warning Score2 (NEWS2, a multiparametric score system), partial pressure of oxygen in arterial blood/fraction of inspired oxygen (P/F ratio), C‐reactive protein, and blood cell count were selected. Results In 64 patients, age (direct relationship), P/F, and platelet number (inverse relationship) independently accounted for 43% of the acute phase duration of the disease (p |
| Databáze: | OpenAIRE |
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