Prevalence of Symptoms More Than Seven Months After Diagnosis of Symptomatic COVID-19 in an Outpatient Setting
| Autor: | Nehme, Mayssam, Braillard, Olivia Thanh-Lan, Chappuis, François, Courvoisier, Delphine, Guessous, Idris, CoviCare Study Team |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Adult
Male Pediatrics medicine.medical_specialty Time Factors Coronavirus disease 2019 (COVID-19) Adolescent MEDLINE Disease COVID-19 / epidemiology Interviews as Topic Olfaction Disorders Young Adult Health Surveys / methods Post-Acute COVID-19 Syndrome Ambulatory care Internal Medicine Ambulatory Care Prevalence Medicine Humans Young adult Grading (education) Fatigue ddc:613 COVID-19 / complications Original Research ddc:616 business.industry SARS-CoV-2 Headache COVID-19 General Medicine Middle Aged Health Surveys Dyspnea / virology Fatigue / virology Telephone Institutional repository Dyspnea Headache / virology Olfaction Disorders / virology Structured interview Female Self Report business COVID-19 / diagnosis |
| Zdroj: | Annals of Internal Medicine Annals of internal medicine, Vol. 174, No 9 (2021) pp. 1252-1260 |
| ISSN: | 1539-3704 0003-4819 |
| Popis: | Coronavirus disease 2019 (COVID-19) can lead to long-term health effects. This article systematically characterizes the prevalence and longitudinal evolution of COVID-19 symptoms more than 7 months after diagnosis among 410 relatively healthy, nonhospitalized patients. Visual Abstract. Prevalence of Symptoms More Than 7 Months After Symptomatic COVID-19. Coronavirus disease 2019 (COVID-19) can lead to long-term health effects. This article systematically characterizes the prevalence and longitudinal evolution of COVID-19 symptoms more than 7 months after diagnosis among 410 relatively healthy, nonhospitalized patients. Visual Abstract. Prevalence of Symptoms More Than 7 Months After Symptomatic COVID-19. Coronavirus disease 2019 (COVID-19) can lead to long-term health effects. This article systematically characterizes the prevalence and longitudinal evolution of COVID-19 symptoms more than 7 months after diagnosis among 410 relatively healthy, nonhospitalized patients. Background: With millions of SARS-CoV-2 infections worldwide, increasing numbers of patients are coming forward with long-term clinical effects of the disease lasting several weeks to months. Objective: To characterize symptoms 7 to 9 months after diagnosis of COVID-19. Design: Self-reported surveys and semistructured telephone interviews at enrollment and 30 to 45 days and 7 to 9 months from diagnosis. Setting: From 18 March to 15 May 2020, symptomatic persons who tested positive for SARS-CoV-2 at the Geneva University Hospitals were followed by CoviCare, a virtual, clinical, outpatient follow-up program. Persons were contacted again at 30 to 45 days and 7 to 9 months from diagnosis. Participants: Persons who were a part of the CoviCare program from 18 March to 15 May 2020. Measurements: A standardized interview of symptoms consistent with COVID-19, with grading of intensity. Results: Of the 629 participants in the study who completed the baseline interviews, 410 completed follow-up at 7 to 9 months after COVID-19 diagnosis; 39.0% reported residual symptoms. Fatigue (20.7%) was the most common symptom reported, followed by loss of taste or smell (16.8%), dyspnea (11.7%), and headache (10.0%). Limitation: Limitations include generalizability and missing data for 34.8% of participants. Conclusion: Residual symptoms after SARS-CoV-2 infection are common among otherwise young and healthy persons followed in an outpatient setting. These findings contribute to the recognition of long-term effects in a disease mostly counted by its death toll to date by promoting communication on postacute sequelae of SARS-CoV-2 and encouraging physicians to continue long-term monitoring of their patients. Primary Funding Source: None. |
| Databáze: | OpenAIRE |
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