Nephrotic syndrome in the course of type 1 diabetes mellitus and systemic lupus erythematosus with secondary antiphospholipid syndrome – diagnostic and therapeutic problems. A case-based review
| Autor: | Radosław Jeleniewicz, Maria Majdan, Dorota Suszek, Aleksandra Graca |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
diabetes mellitus type 1
medicine.medical_specialty medicine.drug_class Immunology Lupus nephritis Nephropathy Rheumatology immune system diseases Diabetes mellitus Biopsy medicine Immunology and Allergy skin and connective tissue diseases Type 1 diabetes Kidney medicine.diagnostic_test nephrotic syndrome business.industry Anticoagulant medicine.disease Dermatology systemic lupus erythematosus medicine.anatomical_structure Medicine business Nephrotic syndrome |
| Zdroj: | Rheumatology, Vol 58, Iss 5, Pp 331-334 (2020) |
| ISSN: | 2084-9834 0034-6233 |
| DOI: | 10.5114/reum.2020.100105 |
| Popis: | Nephrotic syndrome (NS) can be a symptom of many autoimmune, metabolic, or infectious diseases. Kidney involvement is often observed in the course of diabetes mellitus (DM) and systemic lupus erythematosus (SLE). The development of NS with coexisting SLE and DM generates serious diagnostic problems. In this paper, the authors present diagnostic and therapeutic dilemmas in a patient with long-lasting DM, SLE, and secondary antiphospholipid syndrome, in whom NS symptoms appeared. Histopathological examination of the kidney confirmed the diagnosis of lupus nephritis. Immunosuppressive and anticoagulant drugs were used. The authors demonstrated that the character of morphologic lesions in the kidney biopsy can help in diagnosis, nephropathy classification, and further therapeutic decisions, which are distinct in both diseases. |
| Databáze: | OpenAIRE |
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