Increased incidence of co-infection in critically ill patients with influenza

Autor: Alejandro Rodríguez, Antoni Torres, Lieuwe D. J. Bos, Ignacio Martin-Loeches, Jean Louis Vincent, Jordi Solé-Violán, Marcus J. Schultz, Francisco Álvarez-Lerma
Přispěvatelé: Intensive Care Medicine, ACS - Heart failure & arrhythmias
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Intensive care medicine, 43(1), 48-58. Springer Verlag
Intensive Care Medicine
ISSN: 0342-4642
Popis: Co-infection is frequently seen in critically ill patients with influenza, although the exact rate is unknown. We determined the rate of co-infection, the risk factors and the outcomes associated with co-infection in critically ill patients with influenza over a 7-year period in 148 Spanish intensive care units (ICUs). This was a prospective, observational, multicentre study. Influenza was diagnosed using the polymerase chain reaction. Co-infection had to be confirmed using standard bacteriological tests. The primary endpoint of this analysis was the presence of community-acquired co-infection, with secondary endpoints including ICU, 28-day and hospital mortality. Of 2901 ICU patients diagnosed with influenza, 482 (16.6 %) had a co-infection. The proportion of cases of co-infection increased from 11.4 % (110/968) in 2009 to 23.4 % (80/342) in 2015 (P
Databáze: OpenAIRE