Recent advances in pyrazole synthesis employing diazo compounds and synthetic analogues

Autor: Sanoop P. Chandrasekharan, Anamika Dhami, Sandeep Kumar, Kishor Mohanan
Rok vydání: 2022
Předmět:
Zdroj: Organic & Biomolecular Chemistry. 20:8787-8817
ISSN: 1477-0539
1477-0520
Popis: Pyrazole is an essential structural component of many pharmaceuticals and agrochemicals. The synthesis of pyrazoles has been a subject of intense research for several decades. Many transformations are now available to conveniently access pyrazoles from readily available starting materials. Conventionally, the synthesis of pyrazoles involves the condensation reaction of hydrazines with 1,3-dicarbonyl compounds or their synthetic equivalents and 1,3-dipolar cycloaddition reactions of diazo compounds with dipolarophiles. The present review provides comprehensive information on the development of synthetic approaches to access pyrazoles
Databáze: OpenAIRE