The effect of balloon angioplasty on hypertension in atherosclerotic renal-artery stenosis
| Autor: | Herman Pieterman, Ad Dees, Brigit C. Van Jaarsveld, Arie J. Man in 't Veld, Jaap Deinum, Cornelis T. Postma, Maarten A.D.H. Schalekamp, Frans H.M. Derkx, Pieta Krijnen, Arend J.J. Woittiez, A. K. M. Bartelink |
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| Přispěvatelé: | Internal Medicine, Public Health, Radiology & Nuclear Medicine |
| Rok vydání: | 2000 |
| Předmět: |
Creatinine
medicine.medical_specialty Percutaneous business.industry medicine.medical_treatment Renal function Flash pulmonary edema General Medicine medicine.disease chemistry.chemical_compound Stenosis Blood pressure chemistry Angioplasty medicine.artery Internal medicine Cardiology Renovasculaire hypertensie Medicine Renal artery Renovascular hypertension business |
| Zdroj: | The New England Journal of Medicine, 342, 1007-1014 New England Journal of Medicine, 342(14), 1007-1014. Massachussetts Medical Society The New England Journal of Medicine, 342, pp. 1007-1014 |
| ISSN: | 0028-4793 |
| DOI: | 10.1056/nejm200004063421403 |
| Popis: | Background Patients with hypertension and renal-artery stenosis are often treated with percutaneous transluminal renal angioplasty. However, the long-term effects of this procedure on blood pressure are not well understood. Methods We randomly assigned 106 patients with hypertension who had atherosclerotic renal-artery stenosis (defined as a decrease in luminal diameter of 50 percent or more) and a serum creatinine concentration of 2.3 mg per deciliter (200 μmol per liter) or less to undergo percutaneous transluminal renal angioplasty or to receive drug therapy. To be included, patients also had to have a diastolic blood pressure of 95 mm Hg or higher despite treatment with two antihypertensive drugs or an increase of at least 0.2 mg per deciliter (20 μmol per liter) in the serum creatinine concentration during treatment with an angiotensin-converting–enzyme inhibitor. Blood pressure, doses of antihypertensive drugs, and renal function were assessed at 3 and 12 months, and patency of the renal artery was ... |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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