Laboratory Examination of Syphilis
Autor: | Raden Pamudji, Mutia Devi, Fitriani Fitriani, M. Izazi Hari Purwoko, Nofilia Citra Candra, Suroso Adi Nugroho |
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Rok vydání: | 2021 |
Předmět: |
Sexually transmitted disease
syphilis diagnostic RM1-950 urologic and male genital diseases Rapid plasma reagin Serology medicine RC346-429 Treponema medicine.diagnostic_test biology business.industry Fluorescent Treponemal Antibody Absorption bacterial infections and mycoses medicine.disease biology.organism_classification Virology female genital diseases and pregnancy complications Immunoassay biology.protein Syphilis Therapeutics. Pharmacology Neurology. Diseases of the nervous system Antibody business treponema pallidum |
Zdroj: | Bioscientia Medicina: Journal of Biomedicine and Translational Research, Vol 5, Iss 8, Pp 726-745 (2021) |
ISSN: | 2598-0580 |
Popis: | Syphilis, is sexually transmitted disease caused by spirochete Treponema pallidum subsp.pallidum. It have many diverse clinical manifestations that occur in distinct stages. Early diagnosis and management are the main things to prevent transmission and complication. Direct test or morphological observation is the definitive diagnosis of syphilis. This can be done through animal inoculation test, dark field microscopy, direct fluorescence antibody (DFA), and nucleid acid amplification test (NAAT). While the indirect test is a nontreponemal serologic test consist of Wasserman test, venereal disease research laboratory (VDRL), toluidine red unheated serum test (TRUST), unheated serum reagin (USR), rapid plasma reagin (RPR) and treponemal serologic test, such as T. pallidum passive particle agglutination (TPPA), T. pallidum haemagglutination assay (TPHA), fluorescent treponemal antibody absorption (FTA-Abs), enzyme immunoassay (EIA) and rapid test. The algorithm of serologic test can be divided into traditional or reverse. |
Databáze: | OpenAIRE |
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