Image quality improvement using an image-based noise reduction algorithm: initial experience in a phantom model for urinary stones

Autor: Osama Masoud, Philippe Raffy, Frank J. Rybicki, Michael L. Steigner, Stefan Atev, Shadpour Demehri, Scott A. Jacobs, Pascal Salazar
Rok vydání: 2012
Předmět:
Zdroj: Journal of computer assisted tomography. 36(5)
ISSN: 1532-3145
Popis: OBJECTIVE To determine signal-to-noise (SNR), contrast-to-noise ratio, and segmentation error measurements in various low-dose computed tomographic (CT) acquisitions of an anthropomorphic phantom containing urinary stones before and after implementation of a structure-preserving diffusion (SPD) denoising algorithm, and to compare the measurements with those of standard-dose CT acquisitions. METHODS After institutional review board approval, written informed consent was waived and 36 calcium oxalate stones were evaluated after CT acquisitions in an anthropomorphic phantom at variable tube currents (33-137 mA s). The SPD denoising algorithm was applied to all images. Signal-to-noise ratio, contrast-to-noise ratio, and expected segmentation error were determined using manually drawn regions of interest to quantify the effect of the noise reduction on the image quality. RESULTS The value of segmentation error measurements using the SPD denoising algorithm obtained at tube currents as low as 33 mA s (up to 75% dose reduction level) were similar to standard imaging at 137 mA s. The denoised images at reduced doses up to 75% dose reduction have higher SNR than the standard-dose images without denoising (P < 0.005). Stepwise regression showed significant (P < 0.001) effect of dose length product on SNR, and segmentation error measurements. CONCLUSIONS Based on objective noise-related image quality metrics, the SPD denoising algorithm may be useful as a robust and fast tool, and it has the potential to improve image quality in low-dose CT ureter protocols.
Databáze: OpenAIRE