Decontamination of SARS‐CoV‐2 contaminated N95 filtering facepiece respirators using artificial sun lamps
| Autor: | Michelle Sunderman, E.W. Edwards, Young W. Choi, D.C. Glasbrenner, M.J. Mladineo, Aaron W. Richardson, P.H. Keyes, M.W. Howard, J. Boyce, J.K. Middleton |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
business.product_category
N95 Respirators Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) environmental health Target concentration Applied Microbiology and Biotechnology ultraviolet applications Log10 TCID50 03 medical and health sciences Light source Equipment Reuse Humans viruses Respirator disinfection non‐thermal processes Decontamination 030304 developmental biology 0303 health sciences 030306 microbiology SARS-CoV-2 COVID-19 General Medicine Human decontamination Original Articles Contamination Pulp and paper industry Artificial sunlight Environmental science Original Article business Biotechnology |
| Zdroj: | Journal of Applied Microbiology |
| ISSN: | 1365-2672 1364-5072 |
| Popis: | Aims Assess the feasibility of using light from artificial sun lamps to decontaminate N95 filtering facepiece respirators (FFRs) contaminated with SARS‐CoV‐2. Methods and Results FFR coupons or whole FFRs contaminated with 5 log10 TCID50 (target concentration) SARS‐CoV‐2 in culture media, simulated saliva, or simulated lung fluid were dried for 1–2 h, then exposed to light from tanning and horticulture lamps to assess decontamination. Exposed coupons and whole FFRs showed SARS‐CoV‐2 inactivation for all matrices tested. Furthermore, FFRs still met performance specifications after five decontamination cycles. Conclusions It is feasible that artificial sunlight from these sun lamps can be used to decontaminate FFRs provided the UV dose is sufficient and the light is unobstructed. Furthermore, decontamination can be performed up to five times without degrading FFR performance. Significance and Impact of the Study This research shows a proof of principle that artificial sun lamps may be an option to decontaminate SARS‐CoV‐2 on N95 FFRs. UV doses required for inactivation to levels below detection ranged from 4 to 37·8 J cm−2 depending on the light source, virus matrix and FFR type. |
| Databáze: | OpenAIRE |
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