Porosity of temporary denture soft liners containing antifungal agents
| Autor: | Heitor Marques Honório, Vanessa Migliorini Urban, Ana Carolina Pero Vizoto, J. F. M. Lima, Juliana Hotta, Karin Hermana Neppelenbroek, Janaina Gomes Maciel |
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| Přispěvatelé: | Universidade de São Paulo (USP), Universidade Estadual Paulista (Unesp), Universidade Estadual de Ponta Grossa (UEPG) |
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
medicine.medical_specialty
Nystatin Materials science Absorption of water Antifungal Agents Time Factors Surface Properties Denture Partial Temporary Denture Liners Acrylic Resins Microbial Sensitivity Tests Denture liners Denture stomatitis 03 medical and health sciences Calcium Chloride 0302 clinical medicine Polymethacrylic Acids Immersion Materials Testing medicine Porosity General Dentistry Analysis of Variance Chlorhexidine Plasticizer Reproducibility of Results Water 030206 dentistry Surgery lcsh:RK1-715 Ketoconazole Distilled water lcsh:Dentistry Biofilms Anhydrous Anti-infective agents Original Article ANTI-INFECCIOSOS 030217 neurology & neurosurgery Nuclear chemistry medicine.drug |
| Zdroj: | Journal of Applied Oral Science Journal of Applied Oral Science, Volume: 24, Issue: 5, Pages: 453-461, Published: OCT 2016 Web of Science Repositório Institucional da UNESP Universidade Estadual Paulista (UNESP) instacron:UNESP Journal of Applied Oral Science v.24 n.5 2016 Journal of applied oral science Universidade de São Paulo (USP) instacron:USP Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual) Journal of Applied Oral Science, Vol 24, Iss 5, Pp 453-461 |
| ISSN: | 1678-7765 1678-7757 |
| Popis: | Made available in DSpace on 2018-11-26T17:10:38Z (GMT). No. of bitstreams: 0 Previous issue date: 2016-09-01. Added 1 bitstream(s) on 2019-10-09T18:26:23Z : No. of bitstreams: 1 S1678-77572016000500453.pdf: 142973 bytes, checksum: 5940e7785513f4ad7bc83f64755af5b8 (MD5) Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) Incorporation of antifungals in temporary denture soft liners has been recommended for denture stomatitis treatment; however, it may affect their properties. Objective: To evaluate the porosity of a tissue conditioner (Softone) and a temporary resilient liner (Trusoft) modified by minimum inhibitory concentrations (MICs) of antifungal agents for Candida albicans biofilm. Material and Methods: The porosity was measured by water absorption, based on exclusion of the plasticizer effect. Initially, it was determined by sorption isotherms that the adequate storage solution for specimens (65x10x3.3 mm) of both materials was 50% anhydrous calcium chloride (S50). Then, the porosity factor (PF) was calculated for the study groups (n=10) formed by specimens without (control) or with drug incorporation at MICs (nystatin:Ny-0.032 g, chlorhexidine diacetate: Chx-0.064 g, or ketoconazole: Ke-0.128 g each per gram of soft liner powder) after storage in distilled water or S50 for 24 h, seven and 14 d. Data were statistically analyzed by 4-way repeated measures ANOVA and Tukey's test (alpha=.05). Results: Ke resulted in no significant changes in PF for both liners in water over 14 days (p>0.05). Compared with the controls, Softone and Trusoft PFs were increased at 14-day water immersion only after addition of Ny and Chx, and Chx, respectively (p0.05). In all experimental conditions, Softone and Trusoft PFs were significantly lower when immersed in S50 compared with distilled water (p |
| Databáze: | OpenAIRE |
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