Two years outcome in patients with persistent atrial fibrillation after pulmonary vein isolation using the second-generation 28-mm cryoballoon
| Autor: | Mattias Roser, Sebastian Biewener, Verena Tscholl, Saba Suhail, Patrick Nagel, Klaus Lenz, Ulf Landmesser, Barbara Bellmann, Abdullah Khaled-A. Lsharaf, Tina Lin, Andreas Rillig |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Male
medicine.medical_specialty Radiofrequency ablation medicine.medical_treatment Catheter ablation 030204 cardiovascular system & hematology Cryosurgery law.invention Pulmonary vein 03 medical and health sciences 0302 clinical medicine law Physiology (medical) Internal medicine Atrial Fibrillation medicine Fluoroscopy Humans In patient 030212 general & internal medicine Treatment Failure Aged Retrospective Studies medicine.diagnostic_test business.industry Middle Aged Ablation Catheter Treatment Outcome Pulmonary Veins Anesthesia Persistent atrial fibrillation Cardiology Female Cardiology and Cardiovascular Medicine business Anti-Arrhythmia Agents |
| Zdroj: | Heart rhythm. 13(9) |
| ISSN: | 1556-3871 |
| Popis: | Background The efficacy of the second-generation cryoballoon (CB) in patients with paroxysmal atrial fibrillation (AF) has been demonstrated previously. Data on the efficacy of CB ablation in patients with persistent AF are sparse. Objective The aim of this study was to evaluate the 2-year success rate of pulmonary vein isolation in patients with persistent AF using the second-generation CB. Methods Fifty consecutive patients (mean age 64.6 ± 9.9 years; 19 women [38%]) with persistent AF were included in this analysis. The mean follow-up period was 22 ± 11 months. All patients were ablated using the second-generation 28-mm CB. Isolation of the pulmonary veins was confirmed using a spiral mapping catheter. In all patients, follow-up was obtained using 24-hour Holter monitoring or via interrogation of an implanted loop recorder or pacemaker. Results The mean left atrial diameter was 43.6 ± 5.6 mm, the mean CHA2DS2-VASc score was 2.8 ± 1.5, and the mean HAS-BLED score was 2.1 ± 1.2. The mean fluoroscopy time was 25.8 ± 9 minutes, and the mean procedural time was 146.4 ± 37.8 minutes. After 22 ± 11 months, the frequency of arrhythmia recurrence was 22 of 50 (44%) in the overall group (paroxysmal AF 6 of 22 [27%]; persistent AF 16 of 22 [73%]). No major complications occurred. Aneurysma spurium not requiring surgical intervention occurred in 1 (2%) patient. No phrenic nerve palsy was observed. Conclusion Two years' results after pulmonary vein isolation using the second-generation CB in patients with persistent AF are promising. The clinical success rate appears to be similar to the reported success rates of radiofrequency ablation for the treatment of persistent AF. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|