Characterisation of reversed-phase liquid chromatographic columns by chromatographic tests. Evaluation of 36 test parameters: repeatability, reproducibility and correlation
| Autor: | Yvan Vander Heyden, Béla Noszál, Jacques O. De Beer, Zsuzsanna Kovács, Jos Hoogmartens, Eugene Roets, P. Baten, Tímea Iványi, D. Visky, Desire Massart |
|---|---|
| Rok vydání: | 2002 |
| Předmět: |
Reproducibility
Chromatography Chemistry Test procedures Organic Chemistry Analytical chemistry Reproducibility of Results General Medicine Repeatability Biochemistry High-performance liquid chromatography Analytical Chemistry Stationary phase Phase (matter) Spectrophotometry Ultraviolet Round robin test Chromatography High Pressure Liquid |
| Zdroj: | Journal of Chromatography A. 977:39-58 |
| ISSN: | 0021-9673 |
| DOI: | 10.1016/s0021-9673(02)01344-4 |
| Popis: | The European Pharmacopoeia (Ph. Eur.) or other official compendia give only a general description of the stationary phase in the description of a liquid chromatographic method. Therefore the selection of a column giving suitable selectivity presents difficulties. Earlier, a test procedure was proposed that allows measurement of a number of parameters which are reported to be representative for stationary phase characteristics. This paper describes how the test procedure was applied on 69 RP-LC C18 columns. Chromatographic parameters obtained as test results were evaluated, and their repeatability, reproducibility and correlation were examined. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect