'Grey zone' patterns of unexplained endocarditis: still a challenge for clinical decision making
| Autor: | Giorgio Viganò, Antonio Grimaldi, Ottavio Alfieri, Maurizio Taramasso, Francesco Maisano, Maria Grazia Pala, Giovanni La Canna, Stefano Benussi |
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| Přispěvatelé: | Grimaldi, A, Taramasso, M, Maisano, F, La Canna, G, Pala, Mg, Benussi, S, Vigano, G, Alfieri, Ottavio |
| Jazyk: | angličtina |
| Rok vydání: | 2010 |
| Předmět: |
Male
Fastidious organism medicine.medical_specialty medicine.drug_class medicine.medical_treatment Antibiotics Nonbacterial thrombotic endocarditis Diagnosis Differential medicine Humans Endocarditis Radiology Nuclear Medicine and imaging Blood culture Ultrasonography Mitral valve repair medicine.diagnostic_test business.industry Immunologic Tests Bacterial Infections Middle Aged medicine.disease Surgery Acute Endocarditis Cardiology and Cardiovascular Medicine business |
| Popis: | The authors report two cases of unexplained active inflammatory endocarditis with totally different clinical presentations. The patients had undergone previous mitral repair surgery and were referred for multiple soft mobile masses on the mitral ring without clinical or laboratory signs of endocarditis. Serologic screening and blood culture results were negative, including those for specific fastidious bacteria, as well as immunologic tests to rule out "nonbacterial thrombotic endocarditis." Before new surgery, both patients were treated with long-term antibiotic and anticoagulant therapy, with no significant changes in clinical setting and echocardiographic patterns. In neither case was it possible to characterize a specific microorganism: the intraoperative findings were highly evocative of active endocarditis with a macroscopic infiltration of the mitral ring, and culture results from surgical material and valvular tissue were negative. (J Am Soc Echocardiogr 2010;23:221.e1-221.e4.) |
| Databáze: | OpenAIRE |
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