Synthesis of Tetrahydropyrans from Propargyl Alcohols and 1,1-Cyclopropanediesters: A One-Pot Ring-Opening/Conia-ene Protocol

Autor:	Terry P. Lebold, Andrew B. Leduc, Michael A. Kerr
Rok vydání:	2009
Předmět:	Magnetic Resonance Spectroscopy Propanols Chemistry Organic Chemistry Propargyl alcohol Ring (chemistry) Chemical synthesis Mass Spectrometry Catalysis chemistry.chemical_compound Alkynes One pot reaction Propargyl Organic chemistry Lewis acids and bases Ene reaction Pyrans
Zdroj:	The Journal of Organic Chemistry. 74:8414-8416
ISSN:	1520-6904 0022-3263
DOI:	10.1021/jo9019122
Popis:	Lewis acid catalyzed ring opening of 1,1-cyclopropanediesters by the hydroxyl group of a propargyl alcohol sets up a subsequent Conia-ene cyclization to afford substituted tetrahydropyrans in a one-pot, high-yielding procedure.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0172d106ad584ff270cec73cd727c5fb https://doi.org/10.1021/jo9019122 Zobrazit plný text záznamu