Factors associated with level III lymph nodes positive and survival analysis of its dissection in patients with breast cancer
| Autor: | Wenhe Zhao, Heming Zheng, Lixi Luo |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Oncology
medicine.medical_specialty Disease-free survival business.industry lcsh:Surgery Retrospective cohort study lcsh:RD1-811 Lymph node dissection medicine.disease 03 medical and health sciences Dissection Breast cancer 0302 clinical medicine medicine.anatomical_structure 030220 oncology & carcinogenesis Internal medicine Statistical significance medicine 030211 gastroenterology & hepatology Lymph Risk factor business Lymph node Survival analysis |
| Zdroj: | Laparoscopic, Endoscopic and Robotic Surgery, Vol 3, Iss 2, Pp 43-47 (2020) |
| ISSN: | 2468-9009 |
| Popis: | Objective Surgical resection remains the mainstream radical therapy in patients with breast cancer. Given that no consensus has been reached on the exact indication for level III lymph node dissection, the aim of this study is to explore factors associated with level III lymph nodes positive and survival analysis of its dissection in patients with breast cancer. Materials and methods A retrospective study including 61 patients after level I-III dissection via a smaller incision of pectoralis major and 61 patients experiencing only level I and II clearance was performed. Clinicopathological outcomes were compared initially and survival analysis was conducted subsequently. Results No significant differences were presented in baseline and clinicopathological characteristics between the two groups. Ten (16.4%) patients’ level III nodes were proven positive after level III dissection. Positive nodes in level I and II lymph nodes over 9 was demonstrated as an independent predictor of level III nodes positive (OR:200.75 [95% CI:7.77–5187.19], p = 0.001). Although the level I-III lymph node dissection group presented a seemingly better disease-free survival, statistical significance was not detected (p = 0.21). Conclusions This study revealed that having positive nodes in level I and II lymph nodes over 9 was a risk factor of level III lymph nodes positive. But level III lymph node dissection does not offer definite survival benefit. |
| Databáze: | OpenAIRE |
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