Structural and Natural Isotopic Abundance Analysis of Magnesium Gluconate Treated with Energy of Consciousness (The Trivedi Effect®) Using LC-MS and NMR
| Autor: | Benson, Sheila Maureen, Trivedi, Mahendra Kumar, Nayak, Gopal, Branton, Alice, Trivedi, Dahryn |
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| Rok vydání: | 2017 |
| Předmět: |
Fragmentation Pattern of Magnesium Gluconate
Magnesium Gluconate Structural Isotopic Abundance of Magnesium Gluconate Abundance Ratio Analysis Isotope Effects Isotope Effects Structural Properties of Magnesium Gluconate Biofield Trivedi Effect Mahendra Trivedi Consciousness Energy Healing Treatment Magnesium Gluconate Isotopic Abundance Ratio Analysis Isotope Effects Structural Properties of Magnesium Gluconate Novel Potent Enzyme Inhibitors Liquid Chromatography Mass Spectrometry Analysis Nuclear Magnetic Resonance Analysis Fragmentation Pattern of Magnesium Gluconate Liquid Chromatograms of Magnesium Gluconate Therapeutic Responses against Diseases Therapeutic Responses against Immunological Disorders Isotopic Abundance Analysis of Magnesium Gluconate Natural Isotopic Abundance of Magnesium Gluconate Structural Isotopic Abundance of Magnesium Gluconate LC-MS NMR MgC12H22O14 Consciousness Energy Healing Treatment Novel Potent Enzyme Inhibitors Therapeutic Responses against Diseases Isotopic Abundance Analysis of Magnesium Gluconate NMR Natural Isotopic Abundance of Magnesium Gluconate Mahendra Trivedi Therapeutic Responses against Immunological Disorders MgC12H22O14 Liquid Chromatography Mass Spectrometry Analysis Isotopic Abundance Ratio Analysis Biofield Nuclear Magnetic Resonance Analysis Liquid Chromatograms of Magnesium Gluconate |
| ISSN: | 2017-0203 |
| DOI: | 10.5281/zenodo.852255 |
| Popis: | The current research article was aimed to investigate the impact of The Trivedi Effect®- Energy of Consciousness Healing Treatment on the structural properties and isotopic abundance ratio (PM+1/PM and PM+2/PM) of magnesium gluconate using LC-MS and NMR spectroscopy. Magnesium gluconate was divided into two parts – one part was control, and another part was treated with The Trivedi Effect® remotely by eighteen renowned Biofield Energy Healers and defined as the Trivedi Effect® Treated sample. The liquid chromatogram of the control sample showed two peaks at Rt of 1.81 and 2.06 min, whereas the Trivedi Effect® Treated sample displayed these peaks at Rt of 1.79 and 2.03 min. The ESI-MS spectra of the control and the Trivedi Effect® Treated samples revealed the presence of the mass for magnesium gluconate ion in two forms at m/z 447 (adduct form with methanol) and 415 (protonated ion) in positive ionization mode. But, it showed the mass for the gluconate ion at m/z 195 in the negative ionization mode. The fragmentation pattern of magnesium gluconate in the treated sample was notably altered as compared to the control sample. The proton and carbon signals for CH, CH2 and CO groups in the proton and carbon NMR spectra were found almost similar for the control and the treated samples. The isotopic abundance ratio analysis revealed that the isotopic abundance ratio of PM+1/PM (2H/1H or 13C/12C or 17O/16O or 25Mg/24Mg) in two magnesium gluconate ion forms at m/z 447 and 415 in treated sample was significantly decreased by 59.82% and 55.44%, respectively compared with the control sample. The percentage change in the isotopic abundance ratio of PM+2/PM (18O/16O or 26Mg/24Mg) was remarkably decreased in the magnesium gluconate ion at m/z 447 in the treated sample by 78.26% compared with the control sample. Consequently, the isotopic abundance ratio of PM+1/PM (2H/1H or 13C/12C or 17O/16O) in gluconate ion in the treated sample was significantly increased by 37.35% with respect to the control sample. Thus, the Trivedi Effect® treated magnesium gluconate could be valuable for designing better pharmaceutical and/or nutraceutical formulations through its changed physicochemical and thermal properties, which might be providing better therapeutic response against various diseases such as diabetes mellitus, allergies, aging, inflammatory diseases, immunological disorders, and other chronic infections. The treated magnesium gluconate might be helpful to design the novel potent enzyme inhibitors by using its kinetic isotope effects. Mahendra Kumar Trivedi, Alice Branton, Dahryn Trivedi, Gopal Nayak, Aileen Carol Lee, Aksana Hancharuk, Carola Marina Sand, Debra Jane Schnitzer, Rudina Thanasi, Eileen Mary Meagher, Faith Ann Pyka, Gary Richard Gerber, Johanna Catharina Stromsnas, Judith Marian Shapiro, Laura Nelson Streicher, Lorraine Marie Hachfeld, Matthew Charles Hornung, Patricia M. Rowe, Sally Jean Henderson, Sheila Maureen Benson, Shirley Theresa Holmlund, Stephen P. Salters, Parthasarathi Panda, Kalyan Kumar Sethi, Snehasis Jana, Structural and Natural Isotopic Abundance Analysis of Magnesium Gluconate Treated with Energy of Consciousness (The Trivedi Effect®) Using LC-MS and NMR, Chemical and Biomolecular Engineering. Vol. 2, No. 3, 2017, pp. 124-134. doi: 10.11648/j.cbe.20170203.11 |
| Databáze: | OpenAIRE |
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