Turn-on and turn-off fluorescent probes for carbon monoxide detection and blood carboxyhemoglobin determination
| Autor: | Hyun Wook Kang, Seulgi Kim, Doseok Kim, Kwang S. Kim, Nisar Ahmed, Seoncheol Cha, Genggongwo Shi, Taeseung Yoon, Muhammad Yousuf |
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| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
Male
chemistry.chemical_element Bioengineering 010402 general chemistry Photochemistry 01 natural sciences Catalysis Turn (biochemistry) Rats Sprague-Dawley chemistry.chemical_compound Animals Instrumentation Fluorescent Dyes Fluid Flow and Transfer Processes Carbon Monoxide Molecular Structure 010405 organic chemistry Carbazole Process Chemistry and Technology Fluorescence 0104 chemical sciences Rats chemistry Turn off Carboxyhemoglobin Palladium Carbon monoxide |
| ISSN: | 2379-3694 |
| Popis: | Water-soluble, carbazole-based two-photon excitable fluorescent probes MPVC-I (“turn-on”) and MPVC-II (“turn-off”) are rationally designed and synthesized for the selective monitoring of carbon monoxide (CO). Both probes can effectively measure carboxyhemoglobin (HbCO) in the blood of the animals exposed to a CO dose as low as 100 ppm for 10 min. The palladium catalyzed azidocarbonylation reaction was optimized to improve the sensing efficiency. |
| Databáze: | OpenAIRE |
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