| Autor: |
Corssmit, E. P., Heijligenberg, R., Endert, E., Ackermans, M. T., Sauerwein, H. P., Romijn, J. A. |
| Přispěvatelé: |
Other departments |
| Jazyk: |
angličtina |
| Rok vydání: |
1996 |
| Předmět: |
|
| Zdroj: |
Journal of clinical endocrinology and metabolism, 81(9), 3265-3269. The Endocrine Society |
| ISSN: |
0021-972X |
| Popis: |
Interferon-alpha (IFN alpha) concentrations are increased in conditions associated with tissue injury. To investigate the endocrine and metabolic actions of IFN alpha in vivo, we studied eight healthy controls on two occasions, once after administration of 5 million units/m2 rhIFN alpha and once after administration of saline (control). Rates of appearance (Ra) of glucose and glycerol in plasma were measured by infusion of [3-3H]glucose and D5-glycerol, respectively. Energy expenditure and substrate oxidation were determined by indirect calorimetry. IFN alpha induced increases in plasma concentrations of norepinephrine (225 +/- 93%; P |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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