Post-Transplant Diabetes Mellitus After Kidney Transplant in Hispanics and Caucasians Treated with Tacrolimus-Based Immunosuppression
| Autor: | W. Lawrence Beeson, Jerusalem Tilahun, Arputharaj Kore, Sergio Infante, Jill Weissman, Regina Peters, Pedro W. Baron, Lauren Delgado, Michael E. de Vera |
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| Rok vydání: | 2017 |
| Předmět: |
Adult
Male medicine.medical_specialty medicine.medical_treatment Population 030232 urology & nephrology 030230 surgery Tacrolimus White People Body Mass Index 03 medical and health sciences 0302 clinical medicine Postoperative Complications Risk Factors Internal medicine Diabetes mellitus medicine Diabetes Mellitus Humans education Kidney transplantation Retrospective Studies Transplantation education.field_of_study Original Paper business.industry Incidence (epidemiology) Incidence Age Factors Immunosuppression General Medicine Hispanic or Latino Middle Aged medicine.disease Kidney Transplantation Calcineurin Kidney Failure Chronic Female Hispanic Americans business Body mass index Immunosuppressive Agents |
| Zdroj: | Annals of Transplantation |
| ISSN: | 2329-0358 |
| Popis: | BACKGROUND Development of post-transplant diabetes mellitus after kidney transplant (PTDM) significantly increases kidney graft loss and mortality. Several risk factors for PTDM have been reported, including Hispanic ethnicity and the use of calcineurin inhibitors and corticosteroids. The incidence and impact of PTDM in the Hispanic kidney transplant population is unknown. MATERIAL AND METHODS We retrospectively reviewed the medical records of 155 Hispanic and 124 Caucasian patients, who were not diabetics and underwent kidney transplant between January 2006 and December 2011. We analyzed their clinical outcomes at 12 months post-transplant, including the incidence of PTDM, acute rejection rates, and patient and graft survival. RESULTS Hispanics who developed PTDM (n=22) were more than 10 years older and had higher body mass index (BMI) than Hispanics without PTDM (p |
| Databáze: | OpenAIRE |
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