Entropy-based analysis for diffusion anisotropy mapping of healthy and myelopathic spinal cord
| Autor: | TH Li, Chunyi Wen, Keith D.K. Luk, J Cui, Yong Hu |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
Adult
Male medicine.medical_specialty Cord Entropy Cognitive Neuroscience Information Theory computer.software_genre Spinal Cord Diseases Diffusion Anisotropy Young Adult Region of interest Voxel Fractional anisotropy Image Processing Computer-Assisted Humans Medicine Aged Echo-Planar Imaging business.industry Middle Aged Spinal cord Surgery Diffusion Tensor Imaging medicine.anatomical_structure Spinal Cord Neurology Cervical Vertebrae Anisotropy Female Analysis of variance business Nuclear medicine computer Algorithms Diffusion MRI |
| Zdroj: | NeuroImage. 54:2125-2131 |
| ISSN: | 1053-8119 |
| DOI: | 10.1016/j.neuroimage.2010.10.018 |
| Popis: | The present study utilized diffusion MR imaging and fractional anisotropy (FA) mapping to delineate the microstructure of spinal cord. The concept of Shannon entropy was introduced to analyze the complex microstructure of healthy and injured spinal cords based on FA map. A total of 30 volunteers were recruited in this study with informed consent, including 13 healthy adult subjects (group A, 25±3 years), 12 healthy elderly subjects (group B, 53±7 years) and 5 cervical spondylotic myelopathy (CSM) patients (group C, 53±15 years). Diffusion MRI images of cervical spinal cord were taken using pulsed gradient spin-echo-echo-planar imaging (SE-EPI) sequence with a 3T MR system. The region of interest was defined to cover the spinal cord in FA maps. The Shannon entropy of FA values of voxels in the cord was calculated as well as the average FA values. The significant differences were determined among three groups using one-way ANOVA and post-hoc test. As compared with adult and elderly healthy subjects, the entropy of whole spinal cord was significantly lower in CSM patients (group A: 6.07±0.18; B: 6.01±0.23; C: 5.32±0.44; p |
| Databáze: | OpenAIRE |
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