Interconverting Lanthanum Hydride and Borohydride Catalysts for C=O Reduction and C-O Bond Cleavage
| Autor: | Smita Patnaik, Aaron D. Sadow |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
inorganic chemicals
010405 organic chemistry Hydride chemistry.chemical_element Homogeneous catalysis General Chemistry General Medicine 010402 general chemistry Borohydride 01 natural sciences Medicinal chemistry Catalysis 0104 chemical sciences chemistry.chemical_compound Hydroboration chemistry Lanthanum Homoleptic Bond cleavage |
| Zdroj: | Angewandte Chemie (International ed. in English). 58(8) |
| ISSN: | 1521-3773 |
| Popis: | The high catalytic reactivity of homoleptic tris(alkyl) lanthanum La{C(SiHMe2 )3 }3 is highlighted by C-O bond cleavage in the hydroboration of esters and epoxides at room temperature. The catalytic hydroboration tolerates functionality typically susceptible to insertion, reduction, or cleavage reactions. Turnover numbers (TON) up to 10 000 are observed for aliphatic esters. Lanthanum hydrides, generated by reactions with pinacolborane, are competent for reduction of ketones but are inert toward esters. Instead, catalytic reduction of esters requires activation of the lanthanum hydride by pinacolborane. |
| Databáze: | OpenAIRE |
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