Nephrotoxicity and molecular structure
Autor: | C. R. Green, R. A. Woods, Kathryn N. Ham, I. C. Calder, C. C. Funder, P. J. Williams, John D. Tange |
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Rok vydání: | 1975 |
Předmět: |
Pharmacology
Chromatography Necrosis Aniline Compounds Chemistry Health Toxicology and Mutagenesis Catechols macromolecular substances General Medicine Toxicology Biochemistry Nephrotoxicity Hydroquinones Rats Kidney Tubules Proximal Structure-Activity Relationship Phenols Toxicity medicine Animals Female medicine.symptom Oxidation-Reduction |
Zdroj: | Xenobiotica; the fate of foreign compounds in biological systems. 5(5) |
ISSN: | 0049-8254 |
Popis: | The nephrotoxicity of a number of aminophenols, quinols and catechols has been assessed from the extent of necrosis of proximal convoluted tubules produced by intravenous injection in rats, and the toxicity correlated with the oxidation-reduction potentials of the compounds. |
Databáze: | OpenAIRE |
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