Parechovirus A prevalence in adults in The Netherlands
| Autor: | Lieke Brouwer, Katja C. Wolthers, Dasja Pajkrt |
|---|---|
| Přispěvatelé: | AII - Infectious diseases, Medical Microbiology and Infection Prevention, Paediatric Infectious Diseases / Rheumatology / Immunology, ARD - Amsterdam Reproduction and Development |
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Adult
Male medicine.medical_specialty Pediatrics Genotype Parechovirus Severe disease 03 medical and health sciences Medical microbiology Virology Prevalence medicine Humans Phylogeny Aged Netherlands 030304 developmental biology 0303 health sciences Picornaviridae Infections biology 030306 microbiology Brief Report Human parechovirus General Medicine Middle Aged biology.organism_classification medicine.disease Comorbidity Female |
| Zdroj: | Archives of virology, 165(4), 963-966. Springer Wien Archives of Virology |
| ISSN: | 0304-8608 |
| Popis: | Human parechoviruses (HPeV) of the species Parechovirus A are highly prevalent disease-causing pathogens in children worldwide. HPeVs are capable of causing severe disease in adults as well, but the prevalence in adults may be much lower. The aim of our present study was to determine the prevalence of HPeV in clinical samples from adults sent in for diagnostic procedures in a tertiary hospital in the Netherlands. From a total of 10,645 samples obtained from 6175 patients, 20 samples from 11 patients (0.18%) tested positive for HPeV by RT-PCR. Two patients were positive for HPeV-1, two for HPeV-3, and one for HPeV-6. Six HPeVs could not be typed. Eight of the 11 HPeV-positive patients were immunocompromised. Due to comorbidity, we were unable to attribute the patients’ clinical symptoms to the HPeV infection. The HPeV prevalence in adults found in this study is low compared to HPeV prevalence in children. This may be largely explained by the high seropositivity rates in adults, although there could be other mechanisms involved. Electronic supplementary material The online version of this article (10.1007/s00705-020-04547-0) contains supplementary material, which is available to authorized users. |
| Databáze: | OpenAIRE |
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