Transapical-transcatheter aortic valve implantation using the Edwards SAPIEN 3 valve
| Autor: | Dritan USEINI, Markus SCHLÖMICHER, Blerta BELULI, Hildegard CHRIST, Elias EWAIS, Peter HALDENWANG, Polykarpos PATSALIS, Vadim MOUSTAFINE, Matthias BECHTEL, Justus STRAUCH |
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| Rok vydání: | 2022 |
| Předmět: |
Aged
80 and over Male Time Factors Hemodynamics General Medicine Aortic Valve Stenosis Recovery of Function Prosthesis Design Severity of Illness Index Transcatheter Aortic Valve Replacement Postoperative Complications Treatment Outcome Echocardiography Aortic Valve Heart Valve Prosthesis Humans Surgery Female Cardiology and Cardiovascular Medicine Aged Retrospective Studies |
| Zdroj: | The Journal of cardiovascular surgery. 62(6) |
| ISSN: | 1827-191X |
| Popis: | Scarcely any data has been published on the mid-term effect of transapical-transcatheter aortic valve implantation (TA-TAVI) using the Edwards SAPIEN 3 valve (S3; Edwards Lifesciences Corp., Irvine, CA, USA). We present mid-term clinical and echocardiographic outcomes after TA-TAVI utilizing S3.Between 02/2014-06/2017, 122 elderly patients with severe aortic stenosis underwent TA-TAVI utilizing S3 at our institution. We conducted clinical and echocardiographic follow-up. The mean follow-up was 15 months. All end-point-related outcomes were adjudicated according to Valve Academic Research Consortium-2 definitions.The STS-score of the entire cohort was 6.26±4.6. More than one-third of the patients exhibited severe peripheral artery disease. The 30-d all-cause mortality, all-stroke rate, and myocardial infarction of the entire cohort were 4.1%, 1.6%, and 0.8% respectively. Median survival time of the entire cohort was 35 months. The cumulative mid-term myocardial infarction and stroke rate was 2.6% and 3.5%, respectively. The postoperative moderate/severe paravalvular leakage occurred in 1.6% of cases. At discharge, one-year and two-year postprocedure peak/mean gradients were 16.6±8.3/ 9±5.1 mmHg, 18±6.9/ 10±4.5 mmHg, and 22.2±5.4/ 12.8±4.6 mmHg, respectively. The rate of new pacemaker cases was 14.1%. Acute kidney injury network 2/3 appears, as an independent predictor of mortality.We observed very promising early and mid-term clinical outcomes with a high degree of device success and good hemodynamic performance after TA-TAVI using the S3 in the intermediate risk patient profile. |
| Databáze: | OpenAIRE |
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