Cone-beam CT reconstruction with gravity-induced motion

Autor: Paul J. Keall, Michael Jackson, Soo-Min Heng, William Counter, Ilana Feain, Ricky O'Brien, Stéphanie Corde, Chun-Chien Shieh, Peter Bennett, Jeffrey Barber, Verity Ahern, Paul F. White, Jonathan R Sykes
Rok vydání: 2018
Předmět:
Zdroj: Physics in Medicine & Biology. 63:205007
ISSN: 1361-6560
Popis: Fixed-gantry cone-beam computed tomography (CBCT), where the imaging hardware is fixed while the subject is continuously rotated 360° in the horizontal position, has implications for building compact and affordable fixed-gantry linear accelerators (linacs). Fixed-gantry imaging with a rotating subject presents a challenging image reconstruction problem where the gravity-induced motion is coupled to the subject's rotation angle. This study is the first to investigate the feasibility of fixed-gantry CBCT using imaging data of three live rabbits in an ethics-approved study. A novel data-driven motion correction method that combines partial-view reconstruction and motion compensation was developed to overcome this challenge. Fixed-gantry CBCT scans of three live rabbits were acquired on a standard radiotherapy system with the imaging beam fixed and the rabbits continuously rotated using an in-house programmable rotation cradle. The reconstructed images of the thoracic region were validated against conventional CBCT scans acquired at different cradle rotation angles. Results showed that gravity-induced motion caused severe motion blur in all of the cases if unaccounted for. The proposed motion correction method yielded clinically usable image quality with
Databáze: OpenAIRE