Correction of cerebral ischemia in low-resistant animals with an antistress drug Deltaran
| Autor: | A. L. Antelava, E. V. Koplik, I. V. Gannushkina, I. L. Konorova |
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| Rok vydání: | 2006 |
| Předmět: |
Male
Drug media_common.quotation_subject Glycine Ischemia Electroencephalography General Biochemistry Genetics and Molecular Biology Brain Ischemia Delta Sleep-Inducing Peptide Stress Physiological Animals Medicine Premovement neuronal activity cardiovascular diseases Rats Wistar Survival rate media_common medicine.diagnostic_test business.industry General Medicine medicine.disease Rats Drug Combinations Cerebral blood flow Anesthesia Carotid artery occlusion Delta sleep-inducing peptide business |
| Zdroj: | Bulletin of Experimental Biology and Medicine. 141:288-291 |
| ISSN: | 1573-8221 0007-4888 |
| Popis: | Deltaran decreased the amplitude of EEG slow waves and restored neuronal reactivity after carotid artery occlusion in Wistar rats sensitive to cerebral ischemia. Deltaran had no effect on local cerebral blood flow. This drug increased blood supply to a unit of neuronal activity in the brain of intact animals during the acute stage of cerebral ischemia, provided 100% survival rate of rats with cerebral ischemia, and prevented the development of neurological symptoms in survivors. Animal experiments proved the possibility of correcting cerebral ischemia with antistress drug Deltaran. |
| Databáze: | OpenAIRE |
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