Additional file 4 of Microtubule disruption reduces metastasis more effectively than primary tumor growth

Autor: Thompson, Keyata N., Ju, Julia A., Ory, Eleanor C., Pratt, Stephen J. P., Lee, Rachel M., Mathias, Trevor J., Chang, Katarina T., Lee, Cornell J., Goloubeva, Olga G., Bailey, Patrick C., Chakrabarti, Kristi R., Jewell, Christopher M., Vitolo, Michele I., Martin, Stuart S.
Rok vydání: 2022
DOI: 10.6084/m9.figshare.19181524.v1
Popis: Additional file 4: Fig. S4. Vinorelbine treatment decreases tumor cell reattachment. A) Reattachment efficiency of the MDA-MB-436 TD and BT-549 TD cells treated with Vinorelbine (10 ��M) is significantly lower than vehicle control treated cells (0.1% DMSO). Changes in impedance are apparent as early as 4 h and significant differences continue for 24 h after initial seeding. Representative experiment from three independent experiments; each performed in quadruplicate. B) Representative brightfield images of MDA-MB-436 TD and Bt-549 cells. Images were taken at 10 �� magnification at 0, 24, and 48 h in vehicle control, (0.1% DMSO). Vinorelbine (10 ��M), and Staurosporine(1 ��M). Scale bar = 100 ��m.
Databáze: OpenAIRE