Management of Stage III and IV endometriosis: a 10-year experience
| Autor: | Napolitano C, L. Perniola, Giuseppe Benagiano, Mossa B, Marziani R |
|---|---|
| Rok vydání: | 1994 |
| Předmět: |
Reoperation
Infertility Microsurgery medicine.medical_specialty Endometriosis Pain Medroxyprogesterone Acetate Pregnancy medicine Humans Medroxyprogesterone acetate Stage (cooking) Menstruation Disturbances Retrospective Studies Gynecology Danazol business.industry Pelvic pain Female infertility Obstetrics and Gynecology medicine.disease Combined Modality Therapy Reproductive Medicine Female Laparoscopy medicine.symptom business Infertility Female medicine.drug |
| Zdroj: | European Journal of Obstetrics & Gynecology and Reproductive Biology. 53:199-204 |
| ISSN: | 0301-2115 |
| DOI: | 10.1016/0028-2243(94)90119-8 |
| Popis: | A retrospective analysis is reported of the management of 117 cases of infertility associated with Stage III and IV endometriosis. Combined medico-microsurgical treatment was selected in 75.3% of Stage III cases and in 83.3% of those on Stage IV. Medication consisted of medroxyprogesterone acetate in 26 patients and danazol in the remaining 64. Microsurgery alone was utilized in 24.7% of Stage III patients and in 16.6% of those on Stage IV. Both surgery alone and the combined therapy had a profound positive effect on subjective symptoms: dysmenorrhea, dyspareunia and pelvic pain. Following combined therapy, pregnancy was achieved in 34.4% of all women. Respective figures are 30.7% for medroxyprogesterone acetate (29.4% Stage III and 33.3% Stage IV) and 35.9% for danazol (37.7% Stage III and 27.2% Stage IV). In the group of patients treated by surgery alone, pregnancy occurred in 25.9%. Of the pregnancies in women with Stage III endometriosis, 25 were carried to term and 6 ended with a spontaneous abortion; figures for Stage IV women are 5 and 2, respectively. Second-look laparoscopy was performed in 49 of the 79 patients who failed to conceive, at 12-36 months after treatment; persistent genital pathology, to which infertility could be attributed, was found in 77.5% of them. |
| Databáze: | OpenAIRE |
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