| Autor: |
Howard L. McLeod, Mark J. Ratain, Michael J. Morris, M. Eileen Dolan, Susan G. Dorsey, Michiaki Kubo, Yusuke Nakamura, Michael J. Kelley, Michael A. Carducci, John F. Mahoney, Paula N. Friedman, Deanna L. Kroetz, Ivo Shterev, Phillip G. Febbo, Eric J. Small, Cynthia L. Renn, Flora Mulkey, Stefanie D. Krens, Dorothy Watson, Lois Weisman, Cameron Lassiter, Alexander B. Sibley, Heather E. Wheeler, Yoichi Furukawa, Susan Halabi, Jai Patel, William Kevin Kelly, Chen Jiang, Claudia Wing, Sherrie Lessans, Kouros Owzar, Daniel L. Hertz |
| Rok vydání: |
2023 |
| Popis: |
Peripheral neuronal cells (Peri.4U) treated with docetaxel were found to have a significant decrease in sensitivity for A) mean process lengths but not for B) mean outgrowth intensity or C) relative straightness as measured after 24 hours post-drug treatment. For paclitaxel treatment at the same time point, the cells were also found to have significantly decreased sensitivity for D) relative mean process length and E) mean outgrowth intensity but not for F) relative straightness. Neurite parameters measured with MetaXPress® software were averaged from 3 independent experiments. Error bars represent the standard error of the mean from three independent transfection experiments. NTC = non-targeting control, UT= untransfected control. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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