Draft Genome Sequences of Two Closely Related AflatoxigenicAspergillusSpecies Obtained from the Ivory Coast
| Autor: | Brian M. Mack, Geromy G. Moore, Shannon B. Beltz |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
0301 basic medicine
Aflatoxin B1 Sterigmatocystin genome sequence Aspergillus rambellii Biology Genome 03 medical and health sciences chemistry.chemical_compound Phylogenomics Genetics Heterothallic DNA Fungal Gene Ecology Evolution Behavior and Systematics Whole genome sequencing Comparative Genomic Hybridization Aspergillus mating-type locus phylogenomics Sequence Analysis DNA biology.organism_classification Genome Report Cote d'Ivoire 030104 developmental biology chemistry Multigene Family Aspergillus ochraceoroseus Aspergillus rambellii Genome Fungal |
| Zdroj: | Genome Biology and Evolution |
| ISSN: | 1759-6653 |
| DOI: | 10.1093/gbe/evv246 |
| Popis: | Aspergillus ochraceoroseus and Aspergillus rambellii were isolated from soil detritus in Taï National Park, Ivory Coast, Africa. The Type strain for each species happens to be the only representative ever sampled. Both species secrete copious amounts of aflatoxin B1 and sterigmatocystin, because each of their genomes contains clustered genes for biosynthesis of these mycotoxins. We sequenced their genomes using a personal genome machine and found them to be smaller in size (A. ochraceoroseus = 23.9 Mb and A. rambellii = 26.1 Mb), as well as in numbers of predicted genes (7,837 and 7,807, respectively), compared to other sequenced Aspergilli. Our findings also showed that the A. ochraceoroseus Type strain contains a single MAT1-1 gene, while the Type strain of A. rambellii contains a single MAT1-2 gene, indicating that these species are heterothallic (self-infertile). These draft genomes will be useful for understanding the genes and pathways necessary for the cosynthesis of these two toxic secondary metabolites as well as the evolution of these pathways in aflatoxigenic fungi. |
| Databáze: | OpenAIRE |
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