Acute poststreptococcal glomerulonephritis superimposed on IgA nephropathy
| Autor: | Beom Jin Lim, Y T Shin, Kwang Sun Suh, K R Na, K W Lee |
|---|---|
| Rok vydání: | 2008 |
| Předmět: |
Adult
Male Pathology medicine.medical_specialty Endocapillary proliferative glomerulonephritis Biopsy Prednisolone urologic and male genital diseases Nephropathy Diagnosis Differential Nephritic syndrome Glomerulonephritis Streptococcal Infections medicine Humans Microscopic hematuria Glucocorticoids Proteinuria medicine.diagnostic_test business.industry Glomerulonephritis IGA General Medicine medicine.disease female genital diseases and pregnancy complications Nephrology Immunology Acute Disease Renal biopsy medicine.symptom business Kidney disease |
| Zdroj: | Clinical nephrology. 70(2) |
| ISSN: | 0301-0430 |
| Popis: | Superimposition of poststreptococcal glomerulonephritis (PSGN) on the course of IgA nephropathy (IgAN) is uncommon. A case of PSGN during IgA nephropathy is presented. A 30-year-old man who had alternating gross and microscopic hematuria for 7 months underwent a renal biopsy. The first renal biopsy revealed IgAN with mesangial deposits of IgA and C3. Two months later, the patient suffered generalized edema, proteinuria, hematuria, an increased ASO titer and a decreased C3 level. A second renal biopsy revealed diffuse endocapillary proliferative glomerulonephritis with epimembranous hump-like electron-dense deposits of C3, but the original mesangial IgA deposits had disappeared. A diagnosis of acute PSGN was indicated. Two months after the onset of acute nephritic syndrome, the patient remained asymptomatic, except for microscopic hematuria and proteinuria. Some cases with persistent proteinuria or hematuria after PSGN are probably related to preexisting IgAN. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|