Prevalence and prognostic value of late gadolinium enhancement on CMR in aortic stenosis: meta-analysis
| Autor: | Kestutis Rucinskas, Giedre Balciunaite, Peter Søgaard, Darius Palionis, Tomas Zaremba, Nomeda Valeviciene, Audrius Aidietis, Pranas Šerpytis, Sigita Glaveckaite, Arnas Rimkus, Viktor Skorniakov |
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| Rok vydání: | 2019 |
| Předmět: |
Male
medicine.medical_specialty Aortic Valve Stenosis/diagnostic imaging Magnetic Resonance Imaging/methods Cohort Studies Contrast Media/pharmacokinetics Fibrosis Internal medicine Prevalence medicine Humans Radiology Nuclear Medicine and imaging cardiovascular diseases Aged Neuroradiology medicine.diagnostic_test business.industry Magnetic resonance imaging Interventional radiology General Medicine Odds ratio Middle Aged Prognosis medicine.disease Observational Studies as Topic Stenosis Gadolinium/pharmacokinetics Aorta/diagnostic imaging Meta-analysis embryonic structures Cardiology Female Radiology Image Enhancement/methods business Cohort study |
| Zdroj: | Balciunaite, G, Skorniakov, V, Rimkus, A, Zaremba, T, Palionis, D, Valeviciene, N, Aidietis, A, Serpytis, P, Rucinskas, K, Sogaard, P & Glaveckaite, S 2020, ' Prevalence and prognostic value of late gadolinium enhancement on CMR in aortic stenosis : meta-analysis ', European Radiology, vol. 30, no. 1, pp. 640-651 . https://doi.org/10.1007/s00330-019-06386-3 |
| ISSN: | 1432-1084 0938-7994 |
| DOI: | 10.1007/s00330-019-06386-3 |
| Popis: | The aim of this study was to investigate the prevalence and prognostic value of late gadolinium enhancement (LGE), as assessed by cardiovascular magnetic resonance (CMR) imaging, in patients with aortic stenosis. A systematic search of PubMed and EMBASE was performed, and observational cohort studies that analysed the prevalence of LGE and its relation to clinical outcomes in patients with aortic stenosis were included. Odds ratios were used to measure an effect of the presence of LGE on both all-cause and cardiovascular mortality. Nineteen studies were retrieved, accounting for 2032 patients (mean age 69.8 years, mean follow-up 2.8 years). We found that LGE is highly prevalent in aortic stenosis, affecting half of all patients (49.6%), with a non-infarct pattern being the most frequent type (63.6%). The estimated extent of focal fibrosis, expressed in % of LV mass, was equal to 3.83 (95% CI [2.14, 5.52], p |
| Databáze: | OpenAIRE |
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