Omentopexy for Revascularization of Free Tracheal Grafts in Rats
| Autor: | Hiromi Wada, Yutaka Takahashi, Kenji Inui, Shigeki Hitomi, F. Yamazaki, T. Fukuse, Toshiki Hirata, Kotaro Muro, Hiroyasu Yokomise, Takashi Hirai |
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| Rok vydání: | 1992 |
| Předmět: |
Pulmonary and Respiratory Medicine
medicine.medical_specialty Time Factors medicine.medical_treatment Revascularization Epithelium Omentopexy Abdominal wall Peritoneal cavity medicine Animals Mucosal epithelium Neovascularization Pathologic business.industry Regeneration (biology) respiratory system Rats Inbred F344 Rats Surgery Trachea medicine.anatomical_structure Cardiology and Cardiovascular Medicine business Omentum |
| Zdroj: | The Thoracic and Cardiovascular Surgeon. 40:178-181 |
| ISSN: | 1439-1902 0171-6425 |
| Popis: | In rats, we examined the effect of an omentum wrapping on the vascularization of the trachea and on regeneration of the mucosal epithelium in the very early stage after free tracheal grafting. Two pieces of trachea were obtained from each donor rat. One piece was transplanted into the peritoneal cavity of the recipient rat and wrapped with omentum. The other piece was transplanted subcutaneously into the abdominal wall, without omentopexy. Recipients were sacrificed at random on days 1, 2, 3, and 4 after operation (5 rats/day). The increase of blood vessels rose significantly earlier in the omentopexy tracheas than in those without omentopexy (p less than 0.01), with all the former showing a normal ciliated, columnar epithelium in the membranous region of the trachea on day 4, accompanied by excellent epithelial regeneration in the cartilaginous region. These results suggest that omentopexy causes revascularization to occur earlier and to be completed in a shorter time, and that it also promotes epithelial regeneration following free tracheal grafting. |
| Databáze: | OpenAIRE |
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