Reassessing the impact of smoking on preeclampsia/eclampsia: are there age and racial differences?
| Autor: | Fidelma Rigby, Jen Jen Chang, George A. Macones, Jonathan P. DeShazo, Jerome F. Strauss, David Chelmow |
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| Rok vydání: | 2014 |
| Předmět: |
Epidemiology
Maternal Health lcsh:Medicine Blood Pressure 030204 cardiovascular system & hematology Vascular Medicine Cohort Studies 0302 clinical medicine Pre-Eclampsia Pregnancy Risk Factors Ethnicity Medicine and Health Sciences Eclampsia Clinical Epidemiology 030212 general & internal medicine lcsh:Science Multidisciplinary Obstetrics Smoking 3. Good health Hypertension Gestation Pacific islanders Female Cohort study Maternal Age Research Article Adult medicine.medical_specialty Preeclampsia Ethnic Epidemiology 03 medical and health sciences Young Adult Hypertensive Disorders in Pregnancy medicine Humans Genetic Association Studies business.industry lcsh:R Retrospective cohort study Odds ratio medicine.disease United States Pregnancy Complications Women's Health lcsh:Q business |
| Zdroj: | PLoS ONE PLoS ONE, Vol 9, Iss 10, p e106446 (2014) |
| ISSN: | 1932-6203 |
| Popis: | Objective To investigate the association between cigarette use during pregnancy and pregnancy-induced hypertension/preeclampsia/eclampsia (PIH) by maternal race/ethnicity and age. Methods This retrospective cohort study was based on the U.S. 2010 natality data. Our study sample included U.S. women who delivered singleton pregnancies between 20 and 44 weeks of gestation without major fetal anomalies in 2010 (n = 3,113,164). Multivariate logistic regression models were fit to estimate crude and adjusted odds ratios and the corresponding 95% confidence intervals. Results We observed that the association between maternal smoking and PIH varied by maternal race/ethnicity and age. Compared with non-smokers, reduced odds of PIH among pregnant smokers was only evident for non-Hispanic white and non-Hispanic American Indian women aged less than 35 years. Non-Hispanic Asian/Pacific Islander women who smoked during pregnancy had increased odds of PIH regardless of maternal age. Non-Hispanic white and non-Hispanic black women 35 years or older who smoked during pregnancy also had increased odds of PIH. Conclusion Our study findings suggest important differences by maternal race/ethnicity and age in the association between cigarette use during pregnancy and PIH. More research is needed to establish the biologic and social mechanisms that might explain the variations with maternal age and race/ethnicity that were observed in our study. |
| Databáze: | OpenAIRE |
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