A thermodynamic study of F108 and F127 block copolymer interactions with liposomes at physiological temperature
| Autor: | Obed Andres Solis-Gonzalez, Aarón Rojas-Aguilar, Juan Ramón Avendaño-Gómez |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
food.ingredient
Lipid Bilayers Pharmaceutical Science 02 engineering and technology Calorimetry Polypropylenes 030226 pharmacology & pharmacy 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine food Phosphatidylcholine Yolk Copolymer Liposome Temperature technology industry and agriculture Isothermal titration calorimetry 021001 nanoscience & nanotechnology Monomer chemistry Chemical engineering Liposomes embryonic structures Thermodynamics Polyethylenes 0210 nano-technology |
| Zdroj: | Journal of Liposome Research. 32:32-44 |
| ISSN: | 1532-2394 0898-2104 |
| DOI: | 10.1080/08982104.2020.1865401 |
| Popis: | The interactions of egg yolk phosphatidylcholine liposomes with F108 and F127 triblock copolymers, in the monomer state, were analyzed by isothermal titration calorimetry (ITC) at 37 °C. According to the results, the critical micelle concentration was determined to be 0.4 and 0.04 wt.% for F108 and F127, respectively, by surface tension at 37 °C. According to the results, liposomes/poloxamers were not favoured energetically, since endothermic interactions were observed. However, positive changes in entropy promoted a spontaneous process. F127 had a greater partition coefficient (51.97 ± 1.77 × 10 |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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