Report on G4-Med, a Geant4 benchmarking system for medical physics applications developed by the Geant4 Medical Simulation Benchmarking Group

Autor: Dosatsu Sakata, David Bolst, D. H. Wright, Mihaly Novak, A. Perales, Edward Simpson, Christian Fedon, F. Romano, Paolo Dondero, Luciano Pandola, Ioanna Kyriakou, Bruce A. Faddegon, Toshiyuki Toshito, M. A. Cortés-Giraldo, Dmitri Konstantinov, Marie-Claude Bordage, Anatoly B. Rosenfeld, Luis Sarmiento, Yann Perrot, Pedro Arce, Giacomo Cuttone, Vladimir Ivanchenko, Carlo Mancini-Terracciano, Chihiro Omachi, J. M. Quesada, Sebastien Incerti, Dean L Cutajar, M. Maire, Ioannis Sechopoulos, José Ramos-Méndez, P. Cirrone, A. Le, Jeremy M. C. Brown, Susanna Guatelli, A. Mantero, G. Latyshev, Andrea Dotti, Giada Petringa, Laurent Desorgher, Takashi Sasaki
Přispěvatelé: Universidad de Sevilla. Departamento de Física Atómica, Molecular y Nuclear, Centre de Recherches en Cancérologie de Toulouse (CRCT), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Centre d'Etudes Nucléaires de Bordeaux Gradignan (CENBG), Université Sciences et Technologies - Bordeaux 1-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Laboratoire d'Annecy de Physique des Particules (LAPP), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Université Savoie Mont Blanc (USMB [Université de Savoie] [Université de Chambéry])-Centre National de la Recherche Scientifique (CNRS), Institut de Radioprotection et de Sûreté Nucléaire (IRSN)
Rok vydání: 2021
Předmět:
Monte Carlo method
Geant4
medical physics
CROSS-SECTIONS
030218 nuclear medicine & medical imaging
DOSE POINT KERNELS
0302 clinical medicine
MEV ELECTRONS
benchmarking
Monte Carlo
[PHYS]Physics [physics]
PROTON-THERAPY
Large Hadron Collider
medical applications
Medical simulation
Physics
STOPPING-LENGTH TARGETS
Observable
General Medicine
Benchmarking
3. Good health
Women's cancers Radboud Institute for Health Sciences [Radboudumc 17]
Other Physical Sciences
Nuclear Medicine & Medical Imaging
030220 oncology & carcinogenesis
MULTIPLE-SCATTERING
MONTE-CARLO-SIMULATION
Monte Carlo simulations
radiotherapy
hadrotherapy

Monte Carlo Method
medicine.medical_specialty
Oncology and Carcinogenesis
Biomedical Engineering
Article
03 medical and health sciences
Regression testing
medicine
Web application
Medical physics
Computer Simulation
BACKSCATTERING COEFFICIENT
Radiometry
radiotherapy
business.industry
THICK TARGETS
hadrotherapy
Reference data
NEUTRON YIELDS
business
Zdroj: Medical Physics, 48, 1, pp. 19-56
Medical Physics, 48, 19-56
Medical physics, vol 48, iss 1
Med Phys
Med.Phys.
Med.Phys., 2021, 48 (1), pp.19-56. ⟨10.1002/mp.14226⟩
idUS. Depósito de Investigación de la Universidad de Sevilla
instname
ISSN: 2016-7768
0094-2405
Popis: Background: Geant4 is a Monte Carlo code extensively used in medical physics for a wide range of applications, such as dosimetry, micro- and nanodosimetry, imaging, radiation protection, and nuclear medicine. Geant4 is continuously evolving, so it is crucial to have a system that benchmarks this Monte Carlo code for medical physics against reference data and to perform regression testing. Aims: To respond to these needs, we developed G4-Med, a benchmarking and regression testing system of Geant4 for medical physics. Materials and Methods: G4-Med currently includes 18 tests. They range from the benchmarking of fundamental physics quantities to the testing of Monte Carlo simulation setups typical of medical physics applications. Both electromagnetic and hadronic physics processes and models within the prebuilt Geant4 physics lists are tested. The tests included in G4-Med are executed on the CERN computing infrastructure via the use of the geant-val web application, developed at CERN for Geant4 testing. The physical observables can be compared to reference data for benchmarking and to results of previous Geant4 versions for regression testing purposes. Results: This paper describes the tests included in G4-Med and shows the results derived from the benchmarking of Geant4 10.5 against reference data. Discussion: Our results indicate that the Geant4 electromagnetic physics constructor G4EmStandardPhysics_option4 gives a good agreement with the reference data for all the tests. The QGSP_BIC_HP physics list provided an overall adequate description of the physics involved in hadron therapy, including proton and carbon ion therapy. New tests should be included in the next stage of the project to extend the benchmarking to other physical quantities and application scenarios of interest for medical physics. Conclusion: The results presented and discussed in this paper will aid users in tailoring physics lists to their particular application. Ministerio de Economía y Competitividad FPA2016-77689-C2-1-R National Institutes of Health U24CA215123 France-Greece PICS 8235 European Space Agency 4000126645/19/NL/BW Australian Research Council ARC DP170100967, DP170102423 Susan G Komen Foundation for the Cure IIR13262248
Databáze: OpenAIRE