Radiological and Histological Correlation in Small Cell Neuroendocrine Carcinoma of the Breast: A Case Report
| Autor: | Eyhab A. Elobeid, Maha Gharaibeh, Lama A. Bataineh, Mohammed Alorjani, Mwaffaq El-Heis |
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| Rok vydání: | 2021 |
| Předmět: |
Adult
medicine.medical_specialty Breast Cancer 3 Breast Neoplasms Small-cell carcinoma Breast cancer Breast cancer 3 Biopsy medicine Carcinoma Humans Mammography Breast Carcinoma Small Cell skin and connective tissue diseases medicine.diagnostic_test business.industry Cancer Articles General Medicine medicine.disease Carcinoma Neuroendocrine Mastitis Female Radiology business |
| Zdroj: | The American Journal of Case Reports |
| ISSN: | 1941-5923 |
| DOI: | 10.12659/ajcr.932274 |
| Popis: | Patient: Female, 39-year-old Final Diagnosis: Primary neuroendocrine small cell carcinoma of the breast Symptoms: Left breast mass • recurrent mastitis Medication: — Clinical Procedure: — Specialty: Pathology • Radiology Objective: Rare disease Background: Primary breast small cell neuroendocrine carcinoma is a rare subtype of breast cancer with about 57 cases reported in the literature. This rare type of cancer represents about 0.1% of breast carcinomas. Recently, the World Health Organization defined this type of cancer as a separate entity from other breast cancer types. The diagnosis of this type of cancer in the breast is difficult because the histological pattern is similar to the small cell neuroendocrine carcinoma of other more common primary sites of origin, including the lung. Case Report: A 39-year-old woman presented to our hospital with a left breast mass and recurrent mastitis. Physical examination revealed a painless lump in her left breast with a brown-colored discharge from the nipple, and her child refused breastfeeding from the left breast. A high-density well-defined rounded mass was observed upon mammography in the upper lateral aspect of the left breast. This mass lesion appeared hypoechoic with no posterior acoustic shadowing on ultrasound scan. A core-needle biopsy of the mass was performed and the diagnosis of small cell neuroendocrine carcinoma was rendered after histopathologic examination. Positron emission tomography scanning was helpful in the exclusion of primary origin from other organ sites; thus, the primary breast origin of the tumor was confirmed. Conclusions: This case report provides a comprehensive approach to diagnose this type of small cell carcinoma originating primarily in the breast. The suspicion of this type of breast cancer should be raised if there is presence of characteristic histopathologic findings with the exclusion of any primary origin from other organ sites by the help of imaging studies. |
| Databáze: | OpenAIRE |
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