Environmental Factors at the Periconceptional Period and the Occurrence of Cleft Lip and Palate in a Midwest Brazil Population

Autor:	Carla Meliso R, Silvestre, Ageo M C, Silva, Renata Cristina Giroto, Ferreira da Silva, Walkiria S, Bittencourt, Alexandre Meireles, Borba, Vander, Fernandes, Cristhiane A L, da Silva
Rok vydání:	2022
Předmět:	Male Cleft Palate Risk Factors Cleft Lip Case-Control Studies Public Health Environmental and Occupational Health Humans Female Pesticides Child Brazil
Zdroj:	Journal of Occupational & Environmental Medicine. 64:e751-e756
ISSN:	1536-5948 1076-2752
Popis:	To investigate the association between periconceptional environmental exposures and the occurrence of cleft lips and palates.This case-control study analyzed 150 mothers of children with cleft lips and palates living in the same city as 250 mothers whose children did not present with this malformation (controls). Environmental exposure data were gathered through a questionnaire (Latin American Collaborative Study of Congenital Malformations methodology).Multivariate analysis revealed that monthly income below minimum wage, having another malformed child, other diseases in the first gestational trimester (urinary infection), use of pesticides in home gardens, and pesticide use in farms close to the home were risk factors associated with the malformation, whereas taking vitamins was a protective factor.Maternal and paternal exposure to pesticides is associated with cleft lip and palate in Mato Grosso State, Brazil.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00e9973b0385c3dfd72684dfe9fab542 https://doi.org/10.1097/jom.0000000000002689 Zobrazit plný text záznamu